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选择性白细胞吸附疗法在治疗炎症性肠病中的应用 被引量:5

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摘要 炎症性肠病(IBD)包括溃疡性结肠炎(UC)和克罗恩病(CD),目前常规治疗方法有营养疗法、药物疗法、免疫制剂疗法、外科手术等[1,2]。到目前为止,该病病因和发病机制尚未完全阐明,治疗缺乏特异性,没有治愈的方法[3,4],导致部分顽固性患者病程迁延,反复发作,局部(癌变、大出血、肠穿孔等)和全身(多器官累及)并发症增多,严重危害患者的健康[5,6]。IBD 对社会的影响也非常大,因为它可以发生于幼年而且容易终生不愈,影响患者的生长发育、出现心理问题及失去教育和工作机会,糖皮质激素或免疫抑制药物等治疗会导致继发性的健康问题,外科手术可能导致并发症如肠功能紊乱。因此必须寻找新的更加特异的治疗方法[7]。
出处 《医学新知》 CAS 2015年第4期237-240,245,共5页 New Medicine
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