反复呼吸道感染患儿免疫指标与氧化应激状态的变化

Change of immune indexes and oxidative stress state of children with recurrent respiratory tract infection

目的:观察及分析反复呼吸道感染患儿免疫指标与氧化应激状态的变化情况。方法:选取于本院就诊的75例反复呼吸道感染患儿为观察组,同时期的75例体检健康儿童为对照组,将两组儿童的免疫指标与氧化应激状态相关血清指标进行比较,然后将观察组中男童与女童、轻度、中度及重度患儿的检测结果进行比较。结果:观察组的细胞免疫、红细胞免疫及氧化应激状态相关血清指标均差于对照组,且轻度、中度及重度患儿的检测结果也有明显差异,差异具有统计学意义(P<0.05);而男童与女童之间比较,差异无统计学意义(P>0.05)。结论:反复呼吸道感染患儿免疫指标与氧化应激状态的变化较为明显,轻中重度患儿间的差异也较为明显,但是男童与女童之间的差异不明显。

Objective： To observe and analyze the change situation of immune indexes and oxidative stress state of chil- dren with recurrent respiratory tract infection. Methods.. A total of 75 children with recurrent respiratory tract infection in our hospital from January 2014 to June 2015 were selected as observation group, 75 healthy children with health examination at the same time were selected as control group,. The immune indexes and oxidative stress state related serum indexes of two groups were detected, and the detection results of observation group with boys and girls, mild, moderate and severe disease were compared, Results：The cellular immune and erythroeyte immune and oxidative stress state related serum indexes of observation group were all significantly worse than those of control group,and the detection results of observation group with mild, moderate and severe disease showed significantly differences （all P〈0.05）, while the differences of boys and girls were not significant different, （all P〉0.05）. Conclosion：The change of immune indexes and oxidative stress state of children with recurrent respiratory tract infection are obvious, and the differences of children with mild, moderate and severe disease are obvious too, while the differences of boys and girls are not obvious.