摘要
目的评价通过控制高磷血症的方法在治疗终末期肾脏疾病中的疗效。方法我们通过检索近10年PubMed、Cochrane Database of Systematic Reviews、EMbase、知网、万方数据库中关于控制高磷血症在终末期治疗肾脏疾病的随机对照研究(RCTs),同时筛检纳入文献的参考文献,对纳入研究的方法学进行评价。研究者对文献质量进行严格评价和资料提取,对符合质量标准的RCTs用Review manager 5.0软件进行Meta分析。结果5个RCTs共1528名患者纳入研究,其中治疗组(控制高磷血症)765例,对照组(未控制高磷血症)763例。Meta分析结果表明治疗组患者预防肾性骨病的发生、降低心血管疾病并发症、控制死亡率等方面明显优于对照组,具有统计学差异。结论相比传统治疗方案,控制高磷血症可显著提升终末期肾脏疾病的预后,可作为该疾病患者的治疗方案。
Objetcive Evaluate efficacy in the treatment of end stage renal disease through the control of hyperphosphatemia .Methods We searching 10 years through PubMed , Cochrane Database of Systematic Re-views, EMbase , CNKI, WANFANG Database about Control of hyperphosphatemia treatment in end-stage renal disease of randomized study （ RCTs） , and screening into literature references , evaluate the methodology of the study.Results RCTs a total of 1528 patients were included in the study , including the treatment group （ Control of hyperphosphataemia） 765 cases and control （ do not Control of hyperphosphataemia） 763 cases.Meta-analysis results showed that patients treated with the occurrence of the prevention of renal osteodystrophy , Reduce the complications of cardiovascular disease , Control mortality , with a statistically significant difference . Concluis on Compared to conventional treatment, Control of hyperphosphataemia improved the prognosis of the end-stage renal disease patients , can be used as treatment of patients with the disease .
出处
《湖北科技学院学报（医学版）》
2014年第2期110-113,共4页
Journal of Hubei University of Science and Technology(Medical Sciences)
关键词
高磷血症
治疗
终末期肾脏疾病
Hyperphosphatemia
Treatment
End stage renal disease
