四季抗病毒合剂联合利巴韦林治疗手足口病的临床疗效观察

Clinical curative effect of the four seasons of antiviral agent combined with ribavirin in the treatment of hand-foot-mouth disease

目的观察四季抗病毒合剂联合利巴韦林治疗手足口病的临床疗效。方法选择普通型手足口病患儿56例,随机分为对照组和治疗组各28例。对照组给予常规抗病毒、退热等对因对症处理;治疗组在对照组治疗的基础上加用四季抗病毒合剂口服。结果治疗组的退热时间、口腔溃疡愈合时间、手足疱疹消退时间均短于对照组,疗效优于对照组(P<0.05)。结论四季抗病毒合剂联合利巴韦林治疗手足口病疗效显著,副作用少,值得推广。

Objective To observe the clinical curative effect of the four seasons of antiviral agent combined with ribavirin in the treatment of hand-foot-mouth disease. Methods 56 patients with common hand-foot-mouth disease were randomly divided into two groups,with 28 cases in each group. The control group was given antiviral,antifebrile and other symptomatic treatment. The treatment group was given the four seasons oral antiviral agent based on the same treatment as the contral group. Results The antipyretic time,time of disappearance of oral ulcer,time of dis-appearance of skin rash on hands and feet were shorter in the treatment group than those in the control group. The curative effect of the treatment group was better than that of the control group( P < 0. 05). Conclusion The four seasons of antiviral agent combined with ribavirin is effective in the treatment of hand-foot-mouth disease with less side effects.