纳洛酮治疗肺性脑病33例的疗效观察

Efficacy of Naloxone in the Treatment of 33 Cases With Pulmonary Encephalopathy

目的 观察采用纳洛酮治疗肺性脑病的临床疗效。方法 将我院2010年1月-2014年11月收治的67例肺性脑病患者随机分为观察组与对照组。对照组34例患者给予常规综合疗法,观察组33例患者在对照组治疗基础上加用纳洛酮治疗,对两组治疗后的临床疗效进行分析比较。结果 观察组治疗总有效率87.9%,高于对照组64.7%,差异具有统计学意义（P〈0.05）。结论 应用纳洛酮治疗肺性脑病临床疗效显著,能提高治疗有效率,且用药安全可靠。

Objective To observe the curative effect of naloxone in the treatment of pulmonary encephalopathy. Methods 67 patients with pulmonary encephalopathy were randomly divided into observation group and control group in our hospital from January 2010 to November 2014. Control group of 34 cases with conventional comprehensive therapy,observation group based on 33 patients in the control group therapy combined with naloxone treatment,to analyze the clinical efficacy of the two groups after treatment. Results Observed treatment group total effectiveness 87.9%,obviously higher than that of control group 64.7%,significant difference,statistical y significant（P〈 0.05）. Conclusion Application of naloxone in the treatment of pulmonary encephalopathy clinical curative effect significantly,can significantly improve the treatment efficiency, and drug safety and reliable.