介入治疗法联合肿瘤间质治疗方法对肝癌患者免疫功能的影响分析

The Effect of Interventional Therapy Combined With Interstitial Therapy on the Immune Function of Patients With Liver Cancer

目的：探究介入治疗法联合肿瘤间质治疗方法对肝癌患者免疫功能的影响分析。方法选取自2011年1月～2015年1月我院收治的196例中晚期肝癌患者，随机分为实验组和对照组，各98例。对照组采用经肝动脉化疗栓塞术（TACE）进行治疗，实验组在对照组的基础上联合肿瘤间质治疗。观察两组患者免疫功能指标。结果经过治疗后，实验组患者的 CD3＋和 CD4＋高于对照组，血清 SIL-2R 明显低于对照组，经对比，两组差异具有统计学意义，即P ＜0.05。两组的CD8＋比较，差异不具有统计学意义，即 P ＞0.05。结论采用介入治疗法联合肿瘤间质治疗方法对肝癌患者进行治疗，不仅能够改善患者的免疫功能，还可促进患者身体恢复。

Objective To explore the effect of the treatment of interventional therapy combined with interstitial therapy on the immune function of patients with liver cancer. Methods From January 2011 to January 2015, 196 cases of patients with advanced liver cancer were randomly divided into experimental group and control group, each of 98 cases. The control group was treated with transcatheter arterial chemoembolization （TACE）, and the experimental group was treated with the combination of tumor interstitial therapy based on the control group. Immune function of the two groups were observed. Results After treatment, the CD3＋ and CD4＋ in the experimental group were significantly higher than those in the control group, the serum SIL and 2R were significantly lower than those in the control group, the difference was statistically significant, that is, P〈0.05. The difference of CD8＋ in the two groups was not statistically significant, that is, P〉0.05. Conclusion Interventional therapy for treatment of liver cancer patients, not only can improve the immune function, but also promote the recovery of patients.