钠钾镁钙葡萄糖注射液在前列腺电切手术中的应用

Application of Sodium Potassium Magnesium Calcium and Glucose Injection in Transurethral Electroresection of the Prostate

目的：探讨钠钾镁钙葡萄糖注射液对行经尿道前列腺电切术患者电解质的影响。方法2011年3月～2014年11月间，选取60例在我院行经尿道前列腺电切手术的患者，采用随机数字表法分为两组，R 组和 S 组，R 组30例于术中输注500 ml 乳酸钠林格注射液， S 组30例在术中输注500 ml 钠钾镁钙葡萄糖注射液，分别于术前及术后抽血查电解质。结果 R 组中术后钾（P=0.60）、钠（P=0.21）下降无统计学意义，钙（P=0.00）、镁（P=0.02）下降有统计学意义（P＜0.05），术后氯（P=0.64）轻度升高，但无统计学意义；S 组中术后钾（P=0.62）、钠（P=0.08）、氯（P=0.16）、镁（P=0.13）下降无统计学意义，钙（P=0.01）下降有统计学意义（P ＜0.05）；与 R 组相比，S 组的钙、镁下降幅度更小，两组中均无经尿道电切综合征病例发生。结论在前列腺电切手术中，使用两种晶体液在维持钾钠氯稳定方面，二者作用相似，但对于维持钙镁的稳定，使用钠钾镁钙葡萄糖注射液显得更有益。

Objective To investigate the effects of sodium potassium magnesium calcium and glucose injection on electrolytes in transurethral electroresection of the prostate（TURP）. Methods From Mar 2011 to Nov 2014, 60 patients scheduled for elective TURP were randomly assigned to group R and group S. And 500ml of sodium locate ringer injection（in group R） or sodium potassium magnesium calcium and glucose injection（in group S） was infused during the operations. Blood electrolytes were detected before and after surgery. Results In group R, concentrations of K＋（P=0.60） and Na＋ （P=0.21）were decreased and concentration of Cl- （P=0.64） was increased mildly with no statistics difference, but concentrations of Ca2＋ （P=0.00） and Mg2＋（P=0.02）were decreased with statistics difference （P〈0.05）. In group S, concentrations of K＋ （P=0.62）, Na＋ （P=0.08）, Cl-（P=0.16）, and Mg2＋ （P=0.13） were decreased with no statistics difference, but concentration of Ca2＋ （P=0.01）was decreased with statistics difference （P＆lt;0.05）. The reduction of Ca2＋ and Mg2＋ was smaller in group S than in group R. There was no TURS occurred in both group. Conclusions Two kinds of crystal solution have similar effects on maintenance of K＋, Na＋and Cl- in TURP, but sodium potassium magnesium calcium and glucose injection is more beneficial in maintaining the stabilization of Ca2＋ and Mg2＋. It is worth the clinical promotion.