依达拉奉和尼莫地平片联合治疗急性脑梗塞的临床疗效观察

Clinical Observation of Edaravone and Nimodipine in Treatment of Acute Cerebral Infarction

目的：分析探讨依达拉奉与尼莫通（尼莫地平片）联合治疗急性脑梗塞的临床效果。方法选择我院2005年1月～2006年11月收治的脑梗塞住院患者为研究对象，随机分为对照组与治疗组，对照组32例给予尼莫通治疗，治疗组32例给予依达拉奉＋尼莫通联合治疗，观察两组患者的临床疗效与治疗前后的神经功能缺失评分。结果静脉用药停止1周后，治疗组患者的神经功能缺失评分低于对照组（P＜0.05）。治疗组治疗总有效率达84.4％，高于对照组的62.5％（P ＜0.05）。结论依达拉奉和尼莫通联合治疗急性脑梗塞的疗效明显，能够明显改善患者神经功能的缺损，促使其功能恢复，降低致残率，提高生活质量。

Objective To analyze edaravone with nimodipine the clinical effect of combined treatment of acute cerebral infarction. Methods From January 2005 to November 2006 as the research object, hospitalized patients with cerebral infarction were randomly divided into control group and treatment group, 32 cases were treated nimodipine treatment, the treatment group and 32 cases of edaravone ＋ nimodipine combination therapy, to observe the clinical efficacy of two groups of patients with nerve function score before and after the treatment. Results Intravenous drug use to stop a week later, the treatment group of patients with nerve function defect score significantly lower than the control group （P〈0.05）. Treatment group total effective rate was 84.4%, significantly higher than that of control group 62.5% （P〈0.05）. Conclusion Edaravone and nimodipine the curative effect of combination therapy of acute cerebral infarction, can significantly improve patients with nerve function defect, its functional recovery, reduce morbidity, improve the quality of life.