摘要
胆汁酸是胆汁的主要成分,由胆固醇在肝脏内转化合成。胆汁酸具有调节胆固醇饱和度和排除机体过多胆固醇的作用。胆固醇过饱和是胆固醇结石病发病机制中的重要因素。本文综述胆汁酸代谢与胆固醇结石病发病关系的研究进展。
Bile acid, a major component of bile, is converted from cholesterol in the liver. It regulates the cholesterol saturation and eliminates excessive cholesterol in the body. Cholesterol supersaturation is regarded as an essential factor for pathogenesis of cholesterol gallstone disease. This paper reviewes the progress in metabolism of bile acid and its relation to cholesterol gallstone disease.
出处
《上海医药》
CAS
2015年第18期3-6,共4页
Shanghai Medical & Pharmaceutical Journal
基金
国家自然科学基金(81070367
81270537)
关键词
胆汁酸
胆固醇结石病
肝脏
bile acid
cholesterol gallstone disease
liver
