盐酸舍曲林治疗心肌梗死后焦虑抑郁的临床观察

Clinical observation of sertraline hydrochloride in treatment of anxiety and depression after myocardial infarction

①目的探讨盐酸舍曲林治疗心肌梗死后焦虑抑郁的临床疗效。②方法选择在本院接受住院治疗的76例心肌梗死后焦虑抑郁患者作为研究对象,分别给予氯丙咪嗪治疗与盐酸舍曲林治疗,比较两组治疗效果、负面情绪评分、生活质量等差异。③结果观察组治疗有效率94.74%、躯体功能评分(79.21±6.07)、心理功能评分(58.14±6.33)、社会功能评分(57.32±4.21)、总体生活质量评分(76.41±6.08),明显高于对照组;SAS评分(30.13±7.16)、SDS评分(31.05±9.09)明显低于对照组患者(P<0.05);④结论盐酸舍曲林可以有效提高心肌梗死后焦虑抑郁患者的治疗效果,降低负面情绪评分,提高生活质量。

Objective To analyze clinical efficacy of sertraline hydrochloride in the treatment of anxiety and depression after myocardial infarction.Methods 76 patients with anxiety and depression after myocardial infarction in our hospital were as research subjects, were given clomipramine treatment or sertraline treatment, the treatment effects,negative emotions score, quality of life were compared.Resuits The effective rate was 94.74% ,physical function score was（79.21±6.07）points,mental functions was（58.14±6.33）points,social functioning was（57.32±4.21）points,overall quality of life was（76.41±6.08） ,was significantly higher.SAS score was（30.13±7.16）points,SDS score was（31.05±9.09）points, was significantly lower than that in the control group patients （P 〈0.05）. Conclusion Sertraline hydrochloride can improve anxiety and depression after myocardial infarction and reduce negative emotions score, improve quality of life.