银杏达莫注射液辅助颅内血肿清除术治疗高血压性脑出血的疗效观察

Effect of Ginkgo-damo Injection Combined with Intracranial Hematoma on Patients with Hypertensive Cerebral Hemorrhage

目的:探讨银杏达莫注射液辅助颅内血肿清除术治疗高血压性脑出血的临床效果。方法:选择2013年1月-2015年3月50例高血压性脑出血患者,随机分为观察组和对照组,每组25例。对照组采用小骨窗颅内血肿清除术,观察组在对照组基础上应用银杏达莫注射液治疗,比较两组疗效,记录治疗前、后血清白蛋白(ALB)浓度的变化,观察两组格拉斯哥昏迷评分(GCS)和美国国立卫生院神经功能缺损评分(NIHSS)变化。结果:治疗4周后,观察组疗效高于对照组,但差别无统计学意义(P>0.05),ALB浓度明显高于对照组(P<0.05),GCS评分明显高于对照组(P<0.05),而NIHSS评分明显低于对照组(P<0.05)。结论:银杏达莫注射液辅助颅内血肿清除术治疗高血压性脑出血,可明显改善患者预后,提高临床治疗效果。

Objective：To investigate the effect of ginkgo-damo injection combined with intracranial hematoma on patients with hypertensive cerebral hemorrhage.Methods：50cases of hypertensive cerebral hemorrhage,selected from January 2013 to March 2015,were randomly divided into the observation group and the control group,25 cases in each group.The control group received small bone window evacuation of intracranial hematoma,and the observation group was given ginkgo-damo injection on the base of the control group.The efficacy and the concentration of serum albumin（ALB）were compared in two groups.Glasgow Coma Scale（GCS）and the US National Institutes of Health neurological deficits（NIHSS）were recorded before and after treatment in two groups.Results：At 4weeks after treatment,the efficacy in the observation group was higher than that in control group,but the difference was not statistically significant（P〉0.05）,ALB concentration in the observation group was significantly higher than that in control group（P〈0.05）,GCS score in the observation group was significantly higher than that in control group（P〈0.05）,and NIHSS scores were significantly lower than that in control group（P〈0.05）.Conclusion：Ginkgo-damo injection significantly improved prognosis of intracranial hematoma and clinical outcomes in patients with hypertensive cerebral hemorrhage.