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布林佐胺与马来酸噻吗洛尔治疗青光眼的临床疗效比较

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摘要 目的:探讨布林佐胺与马来酸噻吗洛尔治疗青光眼的临床疗效。方法:选取2012年1月-2014年4月我院收治的青光眼患者67例作为观察对象,按照随机数字表法将患者分为观察组34例和对照组33例,对照组患者采取拉坦前列腺素滴眼液治疗,观察组患者采取布林佐胺联合马来酸噻吗洛尔治疗。观察两组患者眼内压、平均动脉压、心率变化情况,观察两组患者不良反应发生情况。结果:治疗前,两组患者眼内压、平均动脉压、心率差异无统计学意义(P>0.05);治疗后,两组患者眼内压显著低于治疗前,与治疗前比较,差异具有统计学意义(P<0.05);治疗后,观察组患者眼内压显著低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者平均动脉压、心率与治疗前比较,差异无统计学意义(P>0.05)。患者均表现为眼部异物感、干涩等,无其他严重不良反应。结论:布林佐胺联合马来酸噻吗洛尔治疗青光眼可有效改善患者眼内压情况,对动脉压、心率等无影响,无严重不良反应。
作者 甘琨 陈娟
出处 《医学理论与实践》 2015年第17期2342-2343,共2页 The Journal of Medical Theory and Practice
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