摘要
目的:观察健脾补肾方加减治疗消化道恶性肿瘤的临床疗效。方法:选取150例消化道恶性肿瘤患者作为研究对象,随机平均分为治疗组和对照组。对照组予以常规抗肿瘤治疗,观察组在对照组基础上予以健脾补肾方加减口服,连续使用14 d后,比较两组患者免疫学指标、中医临床症状改善情况、生存质量及临床疗效。结果:两组患者治疗后NK细胞、CD3+T淋巴细胞、CD4+T淋巴细胞、CD8+T淋巴细胞、CD4+/CD8+均较治疗前好转(P<0.05),且观察组优于对照组,差异有统计学意义(P<0.05)。观察组治疗后中医症状及生存质量均较对照组明显改善(P<0.05)。临床疗效方面,观察组有效率为88.00%,对照组有效率为74.67%,两组比较,差异有统计学意义(P<0.05)。结论:健脾补肾方加减能提高消化道恶性肿瘤临床疗效,改善患者生存质量,提高免疫力。
Objective:To study the clinical curative effect of Jianpi Bushen Fang in treating digestive tract malignant tumor. Methods:150 cases with digestive tract malignant tumor were randomly divided into treatment group and control group. Control group was given con-ventional anti-tumor treatment and the observation group was given Jianpi Bushen Fang based on the control group. Compared immuno-logical indexes,traditional Chinese medicine clinical symptoms improvement,quality of survival and clinical curative effect after 14 d. Results:The NK cells,CD3 + T lymphocytes,CD4 + T lymphocytes,CD8 + T lymphocytes,CD4 + / CD8 + lymphocytes of two groups were improved than before treatment(P ﹤ 0. 05)and the observation group was better than that of control group,the difference was statisti-cally significant(P ﹤ 0. 05). The TCM symptoms and quality of life of treatment group were significantly improved than that of control group(P ﹤ 0. 05). The effective rate was 88. 00% in treatment group and 74. 67% in control group. The difference was statistically sig-nificant(P ﹤ 0. 05). Conclusion:Jianpi Bushen Fang in treating digestive tract malignant tumor can improve clinical curative effect,im-prove the quality of life and enhance immunity.
出处
《中医学报》
CAS
2015年第9期1239-1241,共3页
Acta Chinese Medicine
基金
河南省科技攻关项目(971200100)
关键词
消化道恶性肿瘤
健脾补肾方
生存质量
digestive tract malignant tumor
jianpi bushen fang
quality of life