C反应蛋白与高血压的关联性研究进展

Research Progress of C-Reactive Protein and Hypertension

大量研究表明高血压是一种炎症性疾病。C反应蛋白作为与炎症有关的急性期蛋白,在炎症与高血压的关联中是被研究最多的。研究表明,C反应蛋白不仅独立相关于高血压,而且与高血压靶器官损害密切相关,支持C反应蛋白是高血压的独立预测因子。也有研究显示,尽管C反应蛋白与高血压相关,但并不能判断其因果关系。现将C反应蛋白与高血压的研究现况进行综述。

There is a growing body of evidence that hypertension is an inflammatory disease. As an acute phase protein which is asso- ciated with inflammation, C-reactive protein is one of the most studied in the relationship of inflammation and hypertension. It has been shown that C-reactive protein is not only related to hypertension but also to end-organ damage in hypertension, which supports the view that C-reac- tive protein is a predictor for hypertension. But other evidence suggests that this viewpoint required further research although C-reactive pro- tein is related to hypertension. So in this review the research progress is summarized.