睡眠障碍与心血管疾病研究新进展

Relationship Between Somnipathy and Cardiovascular Disease

现代社会睡眠障碍变得越来越普遍,有30%~64%人群存在睡眠障碍,因此研究睡眠障碍对机体的影响越发重要。新近研究表明睡眠障碍通过自主神经功能调节失衡、降低葡萄糖耐量、增加皮质醇水平、升高血压、降低心率变异性、增加炎症因子分泌、血脂水平异常等参与冠心病、高血压、心律失常和心力衰竭等心血管疾病的发生、发展及预后。

Somnipathy has become increasingly common in modem society and may affect 30% to 64 % of the general population, therefore research on the long-term consequences of sleep problems has become increasingly important. Recent studies suggest that somnipa- thy could change the balance of the autonomic nervous system, lower the glucose tolerance, increase eortisol levels and blood pressure, de- crease variability in heart rate, generally increase inflammatory markers, make the lipid regulation abnormal and much more. As well, som- nipathy may involve in the occurrence, development and prognosis of coronary atherosclerosis disease, hypertension, cardiac arrhythmia and heart failure.