T2WI均匀低信号子宫肌瘤MR扩散张量成像特点的研究

A study of diffusion tensor imaging characteristics of uterine fibroids with homogeneous hypointense signal on T2WI

目的观察T2WI均匀低信号子宫肌瘤患者的DTI特点,包括与正常肌层比较,及不同部位低信号肌瘤的DTI参数差异。材料与方法将65例子宫肌瘤患者行常规MRI平扫、增强及DTI扫描,共80个T2WI均匀低信号肌瘤,其中42个肌壁间肌瘤、38个浆膜下肌瘤,分别测量肌瘤及正常肌层的MD值、FA值及RA值,将测量数据进行SPSS 19.0独立样本t检验。结果 T2WI均匀低信号子宫肌瘤MD值为(1.275±0.204)×10-3 mm2/s,显著低于正常肌层,FA值及RA值分别为0.465±0.114、0.420±0.110,明显高于肌层;而浆膜下肌瘤与肌壁间肌瘤的MD值、FA值及RA值比较无显著差异。结论 T2WI均匀低信号子宫肌瘤的DTI相关参数参数具有一定特征,与正常肌层存在差异,且生长部位对于子宫肌瘤的DTI特点影响不大。

Objective：To observe the DTI characteristics of uterine fibroids with homogeneous hypointense signal on T2WI, including the comparison with normal muscle layers, and the difference of DTI parameters between fibroids at different location. Materials and Methods： Sixty-five patients with uterine fibroids were performed routine MRI scanning, enhanced scanning and DTI scan. Eighty uterine leiomyomas were analyzed, including 42 intramural hysteromyoma and 38 subserous fibroids. The fractional anisotropy （FA）, mean diffusivity （MD） and relatively anisotropy （RA） of all lesions and normal muscle layers were calculated, all data were analyzed through Independent-Samples t test by SPSS 19.0. Results： MD values of hysteromyomas with homogeneous hypointense signal on T2WI was （1.275±0.204）×10^-3 mm^2/s, which was significantly lower than the myometrium, FA values （0.465±0.114） and RA values （0.420±0.110） were higher than the myometrium, but there was no signiifcant difference between the parameters of subserous ifbroids and intramural hysteromyoma. Conclusions：The DTI characteristics of uterine ifbroids with homogeneous hypointense signal on T2WI had some characteristics, which were different with the normal muscle layer, and the location of hysteromyoma did not have much effect on the characteristics of DTI.