摘要
目的通过ADC值的测量探讨DWI在乳腺浸润性导管癌预后评价中的临床应用价值。材料与方法分析47例病理证实为浸润性导管癌的患者病灶ADC值,并与预后因素进行对照分析。结果乳腺浸润性导管癌ADC平均值为(0.957±0.151)×10-3 mm2/s,组织学分级与ADC值间存在负相关关系(r=0.876,P=0.000);病灶>2 cm组平均ADC值低于≤2 cm组(t=2.600,P=0.013);淋巴结转移阳性组平均ADC值低于阴性组(t=4.123,P=0.000);ER及PR阳性组平均ADC值低于阴性组(t=3.557,P=0.003;t=3.599,P=0.002);HER-2阳性组平均ADC值低于阴性组,但差异无统计学意义(t=1.399,P=0.173)。结论 ADC值与乳腺浸润性导管癌部分预后因素存在相关性,它可能是评价乳腺浸润性导管癌预后的潜在参数。
Objective: To investigate correlations between apparent diffusion coefifcient (ADC) values of invasive ductal carcinoma (IDC) and prognostic factors. Materials and Methods:We examined 47 patients by magnetic resonance imaging (MRI) of breast with pathologically conifrmed IDC and measured the ADC values of each lesion. The mean ADC values were cross-check analyzed with the prognostic factors.Results:The mean ADC value was (0.957±0.151)×10^-3 mm^2/s. The mean ADC values of IDC showed inverse correlation with histological grades (r=0.876, P=0.000) and were signiifcantly lower in the cases with large tumor size (t=2.600, P=0.013), axillary lymph nodes metastasis (t=4.123, P=0.000), ER and PR positive expression (t=3.557, P=0.003. t=3.599, P=0.002). HER-2 expression showed no significant correlation with ADC values (t=1.399, P=0.173). Conclusions:The ADC values were correlated with some prognostic factors and might provide valuable information for the prognosis of IDC.
出处
《磁共振成像》
CAS
CSCD
2015年第9期687-691,共5页
Chinese Journal of Magnetic Resonance Imaging
关键词
癌
导管
乳腺
磁共振成像
Carcinoma,ductal,breast
Magnetic resonance imaging