住院患者抗菌药物使用情况分析

Analysis of Antibiotic Application on Inpatient

目的分析医院住院患者抗菌药物使用情况,为临床合理用药提供参考。方法检阅2014年7月至2015年3月医院住院8 748例患者病历,就抗菌药物使用情况作统计分析。结果 2014年12月至2015年2月抗菌药物使用率下降到60%以内;2014年11月后抗菌药物用药频度(DDDs)值控制在40限定日剂量(DDD)以下,特殊使用级抗菌药物DDDs值2014年11月后显著下降。注射剂抗菌药物数量排名前3位的是注射用盐酸头孢替安(锋替新,30 181支)、注射用哌拉西林钠舒巴坦钠(24 997支)、注射用氟氯西林钠(156 937支);口服抗菌药物数量排名前3位的是阿莫西林克拉维酸钾胶囊(4∶1)、头孢克肟分散片、阿莫西林胶囊;共使用抗菌药物13类,其中头孢菌素类(31.51%)、β-内酰胺酶抑制剂(16.44%)、青霉素类(9.59%)构成比排名前3位。结论经认真落实相关文件,医院抗菌药物使用情况得到了明显改善。

Objective To analyze the use of antibiotics in the hospital, and to provide reference for clinical medicine. Methods Using the system software to retrieve inpatients records of 8 748 cases from July 2014 among March 2015 with the use of antibacterial drugs for statistical analysis. Results From February 2015 to December 2014, the rate of antibacterial fell to less than 60%;after November 2014 the antibacterial DDDs value was controlled below 40 DDDs; third-line antibiotics DDDs value declined significantly after November 2014. The top 3 antibiotics injection were eefotiam hydrochloride for Injection（30 181）, piperacillin sodium and sulbactam sodium for injection（24 997）, flueloxacillin sodium for injection（156 937）, oral antibiotics： amoxicillin and clavulanate potassium capsules （4： 1）, eefixime dispersible tablets（9 520）, amoxicillin capsules. There was 13 major categories antibiotics, including cephalosporins （31.51%）, beta lactamase inhibitor （16.44%） and penicillin （9.59%）. Conclusion After conscientiously implement the ＂national health and family planning commission office on doing a good job in 2014 antibacterial drug clinical application management work of the notice＂, the publicity and implementation the ＂administrative measures for the clinical use of antibacterial drugs＂ are increased and the usage of antibiotics has been significantly improved.