小儿手足口病180例病原监测分析

The Etiology Surveillance and Analysis of Children with hand-foot-mouth disease

目的：了解手足口病的病原体型别及临床特征,为其防治提供依据。方法：回顾性分析广西区妇幼保健院180例HFMD患儿的临床资料。结果：共检出172例阳性病例,阳性率为95.56%;其中EV71阳性病例30例,占阳性病例的17.44%;Cox A16阳性病例72例,占阳性病例的41.86%;2011年儿童EV71、Cox A16阳性率分别为1.79%、67.56%;2012年儿童EV71、Cox A16阳性率分别为47.46%、5.08%;2013年儿童EV71、Cox A16阳性率分别为1.75%、54.39%。结论：手足口病以1~3岁儿童发病人数最多,引起HFMD的主要病原体为EV71和Cox A16,但不同年份的主要病原体型别有差别,其他未分型肠道病毒也占相当比重。

Objective To investigate the pathogens and clinical features of hand -food -mouth disease （HFMD）, and to provide the reference for treatment, prevention and control. Methods Clinical data of 180 cases of HFMD from Guangxi Maternal and Child Health Hospital were analysed retrospectively. Results Among the 180 cases, 172 cases were positive （95.56%）, 30 cases were pos- itive for EV71 （ 17.44% ）, 72 cases were positive for CoxA16 （41.86%） ; the positive rate of EV71, CoxA16 in 2011 were 1.79%, 67. 56% respectively; the positive rate of EV71, CoxA16 in 2012 were 47.46%, 5.08%, the positive rate of EV71, CoxA16 in 2013 were 1.75%, 54. 39%. Conclusion HFMD patients were mainly infants and young children between 1 - 3 years old, EVT1, CoxA16 were the main pathogen causing of HFMD, but there are different mainly pathogens types in different years, and other undiffer- entiated types also accounted for quites small proportion.