植物甾醇的抗肿瘤作用及其机制研究进展

Study on development of anti-tumor effect of phytosterols

植物甾醇是植物中的一种活性成分,近年来国外对其抗肿瘤作用及其机制研究颇多。植物甾醇对结肠癌、乳腺癌和前列腺癌都有预防和治疗作用。其作用机制主要为抑制癌症物质产生,抑制肿瘤细胞生长和繁殖;还可以改变肿瘤细胞的信号传导,抑制肿瘤细胞转移,刺激产生肿瘤免疫应答。

Phytosterols are the active constitutents in plant,which have been researched by anti-tumor effect mechanism abroad recently. Phytosterols have prevention and therapeutical effect on colon cancer, breast cancer and prostate cancer. Its mainly mechanism of action includes the inhibition production of cancer substance, depression of growth and breeding of tumor cell,and it can also affect the signal transduction of tumor cell,depression metastasis of tumor cell and stimulate immune response.