藏族药打箭菊的研究进展

Tibetan Medicine Pyrethrum tatsienense

打箭菊作为藏族药特色品种之一,能清热,消炎,镇痛,燥黄水,治疠热病。现通过查阅相关的本草著作和国内外研究文献,对打箭菊的药材基源、化学成分、药理活性、质量标准等方面的研究进行整理和分析,为其全面开发提供科学依据和理论基础。结果显示,藏族药打箭菊的化学成分包括黄酮、三萜、甾体、有机酸及挥发油等物质,其提取物具有抗炎镇痛、抗心肌缺血、保肝、抗缺氧等药理作用,但药效物质基础及其作用机制还未曾阐明,质量标准及生药学方面的研究也较为薄弱。因此,通过本草考证和使用现状调查,规范打箭菊的名称、品种和基源,进一步结合药理、药效物质基础等的深入系统研究,提高和完善质量标准,为打箭菊的临床用药准确、安全有效提供保障。

Pyrethrum tatsienense, a traditional Tibetan medicine, has effects in clearing heat, resisting inflammation, easing pain and treating grasserie. Domestic and foreign study literatures on raw material source, chemical constituents, pharmacological activities and quality standard of P. tatsienense were analyzed and summarized to provide scientific and theoretical basis for the general development of P. tatsienense. According to the findings, the main chemical constituents of P. tatsienense included essential oil, triterpenes, flavonoids, steroids and organic acids; the extracts of P. tatsienense had anti-inflammatory, analgesic, anti-hypoxia, anti- myocardial ischemia and hepatic protective effects. However, its pharmacodynamic material basis and action mechanism were still unclear, and the pharmacognosy and quality standard of P. tasienense were seldom studied. Therefore, efforts shall be made to standardize the name, varieties and base sources of P. tatsienense through herbalogical studies and current utilization surveys and improve the quality standard of P. tatsienense based on in- depth studies on pharmacology and pharmacodynamic material basis, in order to provide guarantee for the accurate clinical medication and effective safety of P. tatsienense.