摘要
克罗恩病(CD)是一种常发生于结肠、小肠或者胃部的炎症性疾病,病因可能与机体免疫功能缺失有关,但具体机制有待研究。CD的临床症状缺乏特异性,且容易合并其他并发症,严重影响患者的正常生活。除个别患者需要手术治疗外,多数CD患者可采用药物治疗,主要有糖皮质激素、5-氨基水杨酸类、免疫抑制剂、抗肿瘤坏死因子单克隆抗体和肠内营养制剂等。加强对CD患者的日常管理,有助于缓解临床症状,且能够预防相关并发症的发生。
Objective Crohn disease (CD) is a kind of inflammatory bowel disease that often occurs in the colon and small intestine or stomach.The cause may be associated with the body's immune function loss,but the specific mecha- nism needs further research.Clinical symptoms of CD lacks specificity and are easy for merging other complications, which seriously affect the patient's normal life.In addition to the individual need for operation treatment,most patients with CD can use drug therapy,mainly including corticosteroids,5-aminosalicylic acid,immunosuppressants,anti-tumor necrosis factor monoclonal antibody and enteral nutrition preparations and so on.To strengthen the daily management of patients with CD can help to relieve the clinical symptoms,and prevent the emergence of the related complications.
出处
《中国当代医药》
2015年第27期17-21,共5页
China Modern Medicine
关键词
克罗恩病
临床症状
诊断
治疗
管理
Crohn disease
Clinical symptom
Diagnosis
Therapy
Management