摘要
Sonic Hedgehog（SHH）信号通路不仅在胎肺发育中起重要作用，在维持生后肺组织、器官的结构和功能的完整中所发挥的作用也不容忽视。近年来，研究发现SHH信号通路参与肺损伤后修复的过程，提示SHH信号通路可能在肺纤维化中起一定作用。
The role of Sonic Hedgehog（SHH） signaling pathway in embryonic lung development has been recognized. What＇s more, it also plays a key role in postnatal development and maintenance of tissue or organ integrity and function. In recent years, studies have found that SHH signaling pathways are involved in the lung repairing process, suggesting that SHH signaling pathways may play a role in pulmonary fibrosis. This paper reviews the effect of the SHH signaling pathway in pulmonary fibrosis.
出处
《国际儿科学杂志》
2015年第5期527-530,共4页
International Journal of Pediatrics
基金
国家自然科学基金资助项目（81070008、81170016、81470214）
浙江省自然科学基金（Y2100337）
