3Mowat A M. Anatomical basis of tolerance and im- munity to intestinal antigens [J]. Nat Rev Immunol, 2003,3 (4).331 - 341.
4Naik S, Kelly E J, Me Ijer L, et al. Absence of Toll - like receptor- 4 explains endotoxin hyporesponsive- ness in human intestinal epithelium [J]. J. Pediatr Gastroen terol Nutr. ,2001,32(4) :449 -453.
5Sansonetti P J. War and peace at mueosal surfaces[J]. Nat Rev Immunol,2004,4(12) :953 -964.
6Wesemann D R. Microbial colonization influences early B- lineage development in the gut lamina pro- pria[J]. Nature ,2013 (501) : 112 - 115.
7Bessa J, Bachmann M F. T cell - dependent and - independent IgA responses:role of TLR signalling [J]. Immunol Invest,2010 (39) ,407 - 428.
8Wei M. Mice carrying a knock - in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense[J]. Nat. Immunol,2011 (12) :264 - 270.
9Kawamoto S. Foxp3 + T ceils regulate immunoglobu- lin A selection and facilitate diversification of bacte- rial species responsible for immune homeostasis[J]. Immunity ,2014 (41) : 152 - 165.
10Gallo R L, HooperL V. Epithelial antimicrobial de- fence of the skin and intestine[J]. Nat Rev Immu- no1,2012 (12) :503 - 516.
二级参考文献73
1SUAU A,BONNET R,SUTREN M,et al. Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut[ J ]. Appl Environ Microbiol, 1999,65 (11) :4799-4807.
2NICOLE M, ROOS D, MARTIJIN B. Effects of probiotic bacteria on diarrhea,lipid metabolism, and carcinogenesis : a review of papers published between 1988 and 1998[ J]. Am J Clin Nutr,2000,71 (2) :405- 411.
3LANGHENDRIES J P. Early bacterial colonisation of the intestine: why it matters. Ital[ J]. J Pediatr,2006,13 (12) :1526-1534.
4MACCPHERSON A J, HARRIS N L. Interactions between eommensal intestinal bacteria and the immune system [ J ]. Nature Rev Immunol, 2004,4(6) :478-485.
5GRONLUND M M,ARVILOMMI H, KERO P,et al. Importance of interstinal colonization in the maturation of humoral immunity in early infancy:a prospective follow-up study of healthy infants aged 0-6 months [J]. Arch Dis Child,2000,83(3) :186-192.
6BRANDTZAEG P. Mucosal immunity: integration between mother and the breast-fed infant [ J ]. Vaccine ,2003,21 (24) : 3382-3388.
7MOWAT A M. Anatomical basis of tolerance and immunity to intestinal antigens[ J]. Nat Rev Immunol,2003,3 (4) :331-341.
8NAIK S, KELLY E J, MEIJER L, et al. Absence of Toll-like receptor-4 explains endotoxin hyporesponsiveness in human intestinal epithelium [ J]. J Pediatr Gastroenterol Nutr,2001,32 (4) :449-453.
9ORTEGA-CAVA C F, ISHIHARA S, RUMI M A, et al. Strategic compartmentalization of Toll-like receptor 4 in the mouse gut[ J]. J Immunol, 2003,170 ( 8 ) :3977-3985.
10SANSONETTI P J. War and peace at mucosal surfaces [ J]. Nat Rev Immunol,2004,4 (12) :953-964.