摘要
镁合金因具有可降解吸收性、优良的力学性能和生物相容性等优点成为植入医疗器械领域的研究热点,降低镁合金过快的腐蚀速度成为其作为植入医疗器械材料应用的关键。综述了镁合金作为植入医疗器械材料在骨折内固定件、骨组织多孔支架和心血管支架等方面应用的最新研究进展及存在的问题,阐述了通过合金化、提高纯度、表面改性、快速凝固、变形加工、非晶化和制备纳米合金等方法提高镁合金材料耐体液腐蚀性能,并展望了镁合金在植入医疗器械领域中的研究方向和应用前景。
Magnesium alloys have been a hotspot in the field of implanted medical devices due to their biodegradable absorbability, excellent mechanical properties and good biocompatibility. The reduction in their rapid corrosion rates becomes the key to the application of implant medical device materials. In this paper, the latest research progress and the existing problems of magnesium alloys as the material for implantation of medical devices in the fracture internal fixation, bone tissue porous scaffold, and cardiovascular stent are reviewed. Improving corrosion resistant of magnesium alloys by means of alloying, improving purity, surface modification, rapid solidification, deformation processing, non crystallization and preparation of nano alloy technology in body fluid are expounded, and research direction and application prospect of magnesium alloys in the field of implanted medical devices are also expected.
出处
《国际生物医学工程杂志》
CAS
2015年第4期242-246,共5页
International Journal of Biomedical Engineering
基金
新疆维吾尔自治区2015年研究生科研创新项目(XJGR12015138)
关键词
镁合金
骨固定材料
骨组织多孔支架
心血管支架
植入医疗器械
Magnesium alloys
Fracture internal fixation material
Bone tissue porous scaffold
Cardiovascular stent
Implanted medical devices