聚癸二酸丙三醇酯静电纺丝支架的制备及其在组织工程中的应用

Research process of the preparation of electrostatic spinning of poly-glycerol sebacate and the application in tissue engineering

聚癸二酸丙三醇酯(PGS)是一种新型可生物降解弹性体,由于优异的生物学性能、力学性能及可降解性使其广泛应用于心脏、血管、软骨等组织器官的生物医学领域。静电纺丝是一种方便快捷、工艺可控、成本低廉的组织工程支架的制备方法。本文对PGS支架的静电纺丝制备及其应用于组织工程的研究进展进行综述。

Poly-glycerol sebacate （ PGS ） is a novel biodegradable elastomer, it has been widely applied in the biomedical fields of heart, blood vessel and cartilage owing to its excellent biological performance, mechanical property and degradability. Electrostatic spinning is a preparation method of tissue engineering scaffolds with the characteristics of convenience, processing controllability and cost efficiency. In this paper, the author reviewed the research process of electrostatic spinning preparation and the application in the field of tissue engineering.