加压状态下不同规格及不同种类液体流速差异研究

Research on velocity difference between specifications and categories of liquid with pressure infusion

目的:为了拓宽用于加压输液的液体规格范围,应用同种加压输液袋在相同加压状态下研究不同规格及不同种类液体的流速差异。方法:(1)对100、250、500 ml 3种规格生理盐水加压,进行输液实验,记录液体流出速率,比较不同规格液体流速差异;(2)对500 ml生理盐水、葡萄糖注射液(5%、10%、50%)、5%葡萄糖氯化钠注射液、5%碳酸氢钠注射液、10%果糖、706代血浆、20%甘露醇注射液等常用于临床的液体加压,进行输液实验,记录液体流出速率,比较不同种类液体流速差异。结果:(1)加压压强相同时,3种规格的液体输出速率无统计学差异;(2)加压压强相同、规格相同,同种浓度的不同种类的液体输出速率无统计学差异;(3)不同浓度相同种类的液体输出速率有统计学差异,浓度越高,输出速率越慢,浓度越低,输出速率越快。结论:加压输液袋不仅适用于500 ml袋装液体,也适用于100、250 ml的袋装液体。当某种规格的液体较为紧缺时,可采用其他规格的液体替代,并不会造成输液速度的改变。在使用加压输液袋进行输液时,更换不同浓度、不同性质的液体后需进行流速的重新调节。

Objective To explore the velocity difference between specifications and categories of liquid with the same pressure infusion bag in order to widen the specification range of the liquid for pressure infusion. Methods Pressure infu-sion experiments were performed with three specifications of normal saline of 100, 250 and 500 ml to compare the veloci-ties of different specifications of liquid, and with 500 ml normal saline, （5%, 10% and 50%） glucose injection, 5% glu-cose and sodium chloride injection, 5% sodium bicarbonate injection, 10% fructose injection, 706 plasma substitute, 20%mannitol injection and etc to make clear the velocities of different categories of liquid. Results With the same pressure, there were no significant differences between the velocities of three specifications of liquid, and between those of cate-gories of liquid with the same specification and concentration; the difference was significant between the same category of liquid with different concentrations, and the velocity showed a negative correlation with the concentration. Conclusion The pressure infusion bag is compatible with 100, 250 and 500 ml liquid, and the velocity may be constant in case some specification of liquid is replaced by another one. The velocity has to be regulated in case the concentration or category of the liquid changes, when the pressure infusion is performed.