摘要
囊性纤维化(CF)是由编码囊性纤维化跨膜传导调节蛋白(CFTR)的基因突变引起的遗传性疾病。CF在我国发病率低,但是具有死亡率极高、中位生存期短的特点。本文介绍了CFRP在CF中的发病机制,并主要对CF治疗的最新进展做一综述。
Cystic fibrosis （CF） is autosomal-recessive genetic disease, which is caused by mutations in the cystic fibrosis transmembrane conductance regulator （CFTR）. In China, the population of CF patients is small, but CF is life-limiting and is associated with high mortality. The present review primarily focuses on the mechanisms of CF, and makes a brief summary of new treatment strategies.
出处
《海南医学》
CAS
2015年第17期2572-2575,共4页
Hainan Medical Journal
关键词
囊性纤维化
发病机制
囊性纤维化跨膜传导调节蛋白
治疗
Cystic fibrosis （CF）
Mechanisms
Cystic fibrosis transmembrane conductance regulator（CFTR）
Treatment
