摘要
目的:探讨T3/T4值、TRAb和ALP在鉴别育龄期女性Grave’s病和破坏性甲状腺炎中的价值。方法:比较82例Graves’病和32例甲状腺炎患者的T3/T4值、TRAb和ALP水平,应用ROC评价其对Graves’病和甲状腺炎的鉴别价值。结果:Graves’病组T3/T4值、TRAb和ALP较甲状腺炎组均显著升高(P<0.01),3个指标鉴别诊断的灵敏度和特异度良好,其中TRAb的灵敏度和特异度分别达0.878和0.969,3个指标的最佳诊断界点分别为20.29(nmol/μmol)、2.805IU/L和143.5IU/L。结论:T3/T4值、TRAb和ALP简便、安全,可用于育龄期女性甲状腺毒症患者的鉴别诊断,TRAb应作为其首选指标。
Objective:To investigate the values of T3/T4 ratio,TRAb and alkaline phosphatase (ALP) in the differential diagnosis of Graves'disease(GD) and thyrotoxicosis in female patients of child-bearing period. Methods:T3/T4 ratio,TRAb and ALP of 82 patients with GD and 32 patients with thyrotoxicosis were compared, and their values in the differential diagnosis were evaluated by receiver operator characteristic curve. Results: T3/T4 ratio, TRAb and ALP were higher in GD group than those in thyrotoxicosis group(P〈0.01).The three index showed good sensitivity and specificity. Their optimization cut-off values were 20.29(nmol/μmol),2.805 IU/L and 143.5 IU/L respectively while the sensitivity and specificity of TRAb were 0.878 and 0.969 respectively. Conclusion:Because of its convenience and safety, T3/T4 ratio, TRAb and ALP could be used in the differential diagnosis of thyrotoxicosis in female patients of child-bearing period, and TRAb would be prefered.
出处
《西北国防医学杂志》
CAS
2015年第9期585-588,共4页
Medical Journal of National Defending Forces in Northwest China
基金
陕西省科技计划资助项目[2007K15-03(5)]