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bcl-2结合抗凋亡蛋白在食管癌中的表达及意义 被引量:4

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摘要 细胞凋亡和肿瘤发生愈来愈受到人们的关注,认为细胞凋亡缺陷或受阻是肿瘤发生发展的一个重要因素。国内外研究表明bcl-2结合抗凋亡蛋白(BAG-1)是一多功能的抗凋亡蛋白,能够与大量的细胞靶点相互作用来实现其多功能的抗凋亡作用,如作用于Bcl-2、Raf-1和核激素受体等蛋白抑制细胞凋亡,而且通过作用于分子伴侣等多种蛋白分子调节细胞的增生、转录、迁移和运动。
出处 《山西医药杂志》 CAS 2015年第16期1873-1875,共3页 Shanxi Medical Journal
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