阻塞性睡眠呼吸暂停低通气综合征与心血管病随访研究

follow-up:the correlation between obstructive sleep apnea syndromeand and cardiovascular diseases

目的随访阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与心血管疾病的关系。方法通过家访式调查和随访,时间为24年,分析OSAHS组和对照组（无OSAHS组）高血压病、冠心病、心力衰竭、心律失常、心肌病、肺心病、退行性心瓣膜病发生情况。结果 1 868例中,男956例,女912例,随访起点年龄53~82（63±6）岁,其中OSAHS组598（32.0%）例,对照组1 270（68.0%）例。终点发生心血管疾病比较显示,OSAHS组582/598（97.3%）例,对照组发生932/1 270（73.4%）例（P〈0.01）。结论 OSAHS患者发生心血管疾病可能性较一般人群高,提示OSAHS与心血管疾病存在相关性,是心血管疾病的独立危险因素。

Objective AIM Observation of obstructive sleep apnea hypopnea syndrome（OSAHS）patients with weight loss therapy.Methods Investigation and follow-up home visits formula,the time is 24 years,analyzing OSAHS group and the control group（no OSAHS group）, hypertension,coronary heart disease, heart failure,arrhythmias,cardiomyopathy,pulmonary heart disease,degenerative heart valve disease incidence.Results 1 868 cases, male 956 cases,female 912 cases,followed up starting age of 53 ~82（63 ＆#177;6）years,of which 598 OSAHS group（32.0%）patients in the control group of 1 270（68.0%）ca-ses.End comparison shows that cardiovascular disease,OSAHS group 582 /598（97.3%）patients in the control group had 932 /1 270（73.4%）cases（P ＆lt;0.01）.Conclusion OSAHS patients the possibility of cardiovascular disease than the general popula-tion,suggesting that OSAHS correlated with cardiovascular disease,is an independent risk factor for cardiovascular disease.