摘要
器官移植术后血脂异常是器官移植术后心血管疾病及移植物失功的重要危险因素之一。影响器官移植术后血脂变化的因素很多,然而随着器官移植的发展,不同年代影响术后血脂变化的因素也有所改变。本文综述了不同年代抗器官排斥药物包括环孢素、硫唑嘌呤、霉酚酸酯、他克莫司、雷帕霉素(西罗莫司)、激素以及单抗等免疫抑制剂应用的不同对术后受者血脂的影响。
[Summary] Dyslipidemia after organ transplantation is one of the important risk factors of postoperative cardiovascular disease and graft dysfunction. There are many factors that result in postoperative dyslipidemia. However, the factors influencing serum lipid levels are changing with the development of organ transplantation. In this article the effects of different anti-rejection drugs such as cyclosporine, azathioprine, mycophenolate mofetil, tacrolimus, rapamycin ( sirolimus ) , corticosteroids, and monoclonal antibody on dyslipidemia after organ transplantation were summarized in different eras.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2015年第9期816-818,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
不同年代
器官移植
抗排斥药物
血脂异常
Different eras
Organ transplantation
Anti-rejection drugs
Dyslipidemia