乳腺增生症与心理、精神因素关系的回顾性分析

Retrospective Analysis of the Relationship Between Cyclomastopathy and Psychological Factors

目的 探讨和筛选出哪些常见的心理、精神因素是乳腺增生症的危险因素,为乳腺增生症的一级预防提供科学依据,同时为该病的病因学研究提供参考。方法 将2010-01-01～2011-12-31间在秦皇岛市第一医院、秦皇岛市妇幼医院、海港医院体检和乳腺门诊确诊的新发乳腺增生症患者选为病例组;乳腺症状、体征及影像学检查均为阴性者选为对照组。提前培训好调查人员,统一标准,对被调查者进行调查。主要内容包括：一般特征、心理、精神因素、孕产情况、月经史等。所获得的全部资料数据由两人分别重复输入电脑,建立数据库,校验正确后,运用SPSS11.6软件对各变量进行单因素分析,算出卡方值,继而引入多因素模型进行分析,计算OR值,估计OR值的95%可信区间,计算P值。同时分析乳腺增生症与各因素的关联强度。结果 单因素分析：自我调节能力（χ2=8.79,P=0.01）,容易生气（χ2=6.43,P=0.04）,婚姻生活不和谐（χ2=5.54,P=0.02）,精神创伤（χ2=5.25,P=0.02）,人际关系（χ2=6.70,P=0.02）与乳腺增生症有关联。结论 自我调节能力差、爱生气是乳腺增生症的危险因素。

Objective To explore which psychological factors are the major risk factors of cyclomastopathy and provide theory founda- tion for studying the etiology and primary prevention of hyperplasia of mammary gland. Methods A hospital based case - control study was carried out on patients diagnosed as cyclomastopathy in accord with breast surgery and medical examination center were taken as the case group from January, 1 st, 2010 to December, 31 st, 2011 in Qinhuangdao City First Hospital, Qinhuangdao City Women and Children Hos- pital, and Harbour Hospital, and people whose cyclomstopathy, physical sign and imaging examination were negative were regarded as the control group. The self- designed questionnaire were used to collect the information by professional staff on general character, psychological factors, menses and production factor and so on. Two persons built Excel database one by one repeatedly after the collection of all informa- tion. Through using SPSS11.6, each variable was analyzed with single factor to calculate X2 and P value. The OR value of the factors with significant statistic correlation were adjusted using multi - variable logistic regression model, and then the value of odds ratio （OR） and 95% confidence interval （95% CI） were calculated. Results Single factor analysis showed that self-regulatory capability （X2 = 8. 79, P = 0. 01 ）, irritability （X2 = 6. 43, P = 0. 04 ）, martial discord （X： = 5.54, P = 0. 02 ）, mental suffering （X2 = 5.25, P = 0. 02 ）, poor hu- man relationship （X2 = 6. 70,P = 0. 02） were associated with cyclomastopathy. Conclusion Poor self - regulatory capability and irritability are risk factors of cyclomastopathy.