大气纳米颗粒物对人体健康效应的研究进展

Research on advance of health effects of nanoparticles on air pollution in China

大气污染物中细颗粒物的健康危害已经得到证实，其中超细颗粒物（即纳米颗粒物）对人体健康的危害也逐渐得到研究者的关注。本文首先根据我国大气中存在的纳米颗粒物的特点，探讨了其来源和理化特性，然后重点总结了我国大气污染物中常见的纳米颗粒物对机体主要组织器官的负面生物效应和作用机制，最后提出了对大气污染物中纳米颗粒物的研究重点。

The adverse health effects of fine particles in the air pollution has been confirmed, and health consequences induced by ultrafine particles （mass media aerodynamic diameter〈0.1 micrometer）, which was also known as nanoparticles, was drawing an increasing attention by researchers. Firstly, this review discussed the sources and physicochemical characteristics of nanoparticles in the atmosphere in China. And then we focused on the biological effects and potential toxicity mechanisms of some common nanoparticles in the atmosphere on the major tissues and organs. Finally, the research focus of the nano particles in air pollutants was also presented.