妊娠糖尿病治疗对妊娠结局的影响分析

Analysis of the Effect of Treatment on the Pregnancy Outcome in Gestational Diabetes Mellitus

目的深入研究妊娠糖尿病治疗对妊娠结局的影响。方法选取于2012年7月—2015年6月期间在该院接受治疗的妊娠糖尿病孕产妇88例,将孕产妇随机分为对照组(42例)和治疗组(46例)进行对照研究,观察保守治疗和胰岛素治疗的效果并进行比较。结果治疗组孕产妇的剖宫产、妊高征、羊水过多、胎膜早破、产后出血、生殖道感染等围生期并发症发生率均显著低于对照组;同时治疗组围生儿巨大儿、胎儿窘迫、胎儿畸形、胎儿窒息、新生儿窒息、新生儿低血糖等围生期并发症发生率均显著低于对照组,差异有统计学意义(P<0.05)。结论在对妊娠糖尿病孕产妇进行保守治疗的基础上给予胰岛素治疗具有显著的效果,能够显著改善妊娠结局,对降低孕产妇以及围生儿的围生期并发症发生率具有显著的临床作用和意义。

Objective To further study the effect of the treatment on the pregnancy outcome in gestational diabetes mellitus. Methods 88 pregnant women with gestational diabetes mellitus treated in our hospital from July 2012 to June 2015 were selected and randomly divided into the control group（42 cases） and the treatment group（46 cases） for the control study. The control group was given expectant treatment, and the treatment group was treated by insulin based on the expectant treat-ment. And the therapeutic effect was compared between the two groups. Results The incidence of cesarean section, pregnan-cy-induced hypertension syndrome, hydramnion, premature rupture of membranes, postpartum hemorrhage, genital tract in-fection and other perinatal complications was much lower in the treatment group than that in the control group, respectively;the incidence of fetal macrosomia, fetal distress, fetal malformation, fetal asphyxia, neonatal asphyxia, neonatal hypoglycemia and other perinatal complications was much lower in the treatment group than that in the control group, respectively with sta-tistically significant difference （P〈0.05）. Conclusion For pregnant women with gestational diabetes mellitus, the insulin treatment combined with expectant treatment has significant effect, which can obviously improve the pregnancy outcome, re-duce the incidence of perinatal complications in pregnant women and perinatal infants with significant clinical value.