摘要
目的探讨瑞格列奈治疗2型糖尿病的临床疗效。方法选取2012年10月—2014年10月医院收治的206例2型糖尿病患者,按照住院时间分为两组,对照组103例给予二甲双胍和格列本脲治疗,观察组103例给予瑞格列奈治疗,分析总结两组患者的治疗效果和不良反应。结果观察组治疗有效率为97.1%,有2例出现轻微低血糖反应,不良反应发生率为1.9%,对照组治疗有效率为76.7%,有5例出现轻度腹泻,4例出现胃痛或不适,不良反应发生率为8.7%,两组比较差异有统计学意义(P<0.05)。结论瑞格列奈治疗2型糖尿病的临床疗效满意,不良反应少,安全性高,可以明显提高患者的生活质量,值得在临床上大力推广应用。
Objective To investigate the clinical efficacy of repaglinide in treatment of type 2 diabetes mellitus. Methods From October 2012 to 2014, the 10 month hospital 206 cases of type 2 diabetes patients, according to the length of hospital stay were divided into two groups, the control group （103 cases） given metformin and glipizide in the urea treatment, the ob-servation group （103 cases） given repaglinide treatment, analysis and summary of the two groups of patients with therapeutic effect and adverse reaction. Results In the observation group, the effective rate was 97.1%, 2 cases of mild hypoglycemia reaction and adverse reactions occurred rate was 1.9%, the control group, the effective rate was 76.7%, 5 cases had mild diarrhea, 4 cases appeared stomach pain or discomfort and adverse reactions occurrence rate was 8.7%, two groups com-pared with statistical significance（P〈0.05）. Conclusion Repaglinide in the treatment of type 2 diabetes with satisfactory clin-ical efficacy, fewer adverse reactions, high safety, can significantly improve the quality of life of patients, it is worth to pop-ularize in the clinical application.
出处
《糖尿病新世界》
2015年第17期47-49,共3页
Diabetes New World Magazine
