窄带成像内镜在咽喉部恶性肿瘤早期诊断中的应用研究

Clinical application of narrow band imaging in the early diagnosis of malignant tumor in laryngeal part of pharynx under endoscopy

目的评价窄带成像内镜技术在咽喉部恶性肿瘤早期诊断中的应用价值。方法回顾性分析2013年5月至2015年6月就诊于内蒙古北方重工业集团有限公司医院耳鼻喉头颈外科门诊的咽喉部病变患者,将其内镜下白光检查及窄带成像检查结果与病理学结果进行比较并进行统计学分析。结果共纳入203例患者,将其咽喉部恶性病变和癌前病变的临床诊断与病理学结果相比较,结果显示白光检查与窄带成像检查的准确率分别为88.6%和97.0%(P>0.05),敏感性分别为81.8%和97.1%(P<0.05),特异性分别为89.9%和97.0%(P<0.05),阳性预测值分别为61.4%和87.2%(P<0.05),阴性预测值分别为96.2%和99.4%(P>0.05)。结论窄带成像内镜对咽喉部黏膜微血管形态改变的识别能力对于区分咽喉部癌性病变及非癌性病变具有应用价值。

Objective To evaluate the clinical value of narrow band imaging in the early diagnosis of malignant tμmor in laryngeal part of pharynx under endoscopy. Methods Between May 2013 and Jun. 2015, patients with diseases in laryngeal part of pharynx were identified by review of patient records of the E. N. T. under endoscopy in the North Hospital, and their clinical data were analyzed retrospectively. Results 203 cases with diseases in laryngeal part of pharynx were enrolled. The accurate rate, sensitivity, specificity, positive predictive value and negative predictive value of white light and narrow band imaging for the diagnosis of malignant tμmor and precancerous lesions in laryngeal part of pharynx were 88.6% and 97.0%（P〉0.05）,81.8% and 97.1%（P〉0.05）,g9.9% and 97.0%（P〈0.05）,61.4% and 87.2% （ P 〈 0. 005 ） ,96.2% and 99.4% （ P 〉 0.05 ） respectively. Conclusions The high sensitivity, specificity, positive predictive value of narrow band imaging in the early diagnosis of malignant tμmor in laryngeal part of pharynx under endoscopy were helpful and recommended.