摘要
以离子液体为催化剂和反应媒介,将其用于苯酚和丁烯酮的反应中合成覆盆子酮;考察了离子液体阴阳离子结构、离子液体用量、底物配比、反应温度和时间对合成覆盆子酮反应性能的影响.结果表明,以酸性离子液体[BMIM]HSO4为催化剂,n(苯酚)∶n(丁烯酮)=1∶2,25℃反应12 h时,覆盆子酮的产率可达73%.使用酸性离子液体催化合成覆盆子酮具有反应操作简便、后处理简单、未反应的原料和催化剂可以循环使用、不使用任何有毒催化剂和有机溶剂等优点,是一种绿色环保的合成覆盆子酮的新方法.
A green and efficient protocol for the synthesis of raspberry ketone by the reaction of phenol with methyl vinyl ketone in ionic liquid l-butyl-3-methylimidazolium hydrogen sulphate（[BMIM]HSO4）has been developed. The effects of the amount of ionic liquid,temperature,time,and ratio on the reaction were investigated. The results showed that the best yield（73%）could be obtained. The reaction conditions were mild,eliminating the need for toxic and expensive catalysts and volatile organic solvents. Furthermore,the ionic liquid could be easily separated and reused for at least 5 times. The study provided a simple and efficient alternative way for the industrial synthesis of raspberry ketone.
出处
《河南科学》
2015年第9期1516-1519,共4页
Henan Science
关键词
离子液体
苯酚
丁烯酮
覆盆子酮
ionic liquid
phenol
methyl vinyl ketone
raspberry ketone
