广州市2005-2013年戊型病毒性肝炎流行病学分析

Hepatitis E epidemiological analysis in Guangzhou city during 2005-2013

目的了解广州市戊型病毒性肝炎（简称戊肝）发病情况及流行趋势,确定高危人群,为戊肝的预防控制提供数据支持。方法对广州市2005-2013年戊肝发病数据进行描述流行病学分析。结果广州市2005-2013年共报告戊肝病例4 985例,发病率为4.78/10万,发病率2010年前呈逐年上升趋势,后开始下降,病例高度散发。全年均有发生,但在1～5月相对高发;发病率随年龄增长而升高;男女发病率性别比为1.85∶1;各区县年平均发病率在1.78/10万（萝岗区）到8.24/10万（越秀区）之间;职业以离退人员、家务及待业人员为主。结论广州市戊肝防控形势仍然严峻,对重点防治人群要加强卫生宣传教育,采取以控制传染源、切断传播途径为主的综合性防治措施。

Objective To study the epidemic features of hepatitis E, and provide the basis for the strategy of pre- vention. Methods The data of hepatitis E in Guangzhou during 2005 and 2013 was analyzed and de- scribed. Results 4985 sporadic cases were reported in Guangzhou from 2005 to 2013. The total incidence rate was 4. 78/100000, and it increased from 2005 to 2010, then dropped after 2010. Cases were found all the year, but the seasonal peak was from January to May. The incidence increased with age and it was higher in male than female （ 1.85： 1 ） . The district average annual incidence was from 1.78/100000 （ Luogang dis- trict） to 8.24/100000 （Yuexiu district） . The infected people .were mainly retiree andhousework and unem- ployed persons. Conclusions The epidemic situation of hepatitis E in Guangzhou is still serious. Health educa- tion should be strengthening in key control groups, and comprehensive measures should be taken to prevent and control hepatitis E.