理想控制血糖妊娠糖尿病与非妊娠糖尿病孕妇围生结局的比较性研究

The Comparative Study on the Outcome of the Ideal Control of Blood Glucose in Pregnant Women and Non Pregnant Women

目的比较理想控制血糖妊娠糖尿病与非妊娠糖尿病孕妇围生结局之间的差异是否具有统计学意义。方法随机选择近年来血糖控制理想的45例妊娠糖尿病孕妇(观察组)和具有可比性的45例非妊娠糖尿病产妇(对照组)为研究对象,通过对观察组孕妇采用健康教育指导、饮食和运动治疗及(或)应用胰岛素控制血糖在理想范围,比较两组孕妇娠高血压综合征、先兆子痫、剖宫产、难产及软产道损伤、羊水过多、胎膜早破、产后出血、早产、新生儿呼吸窘迫综合征、巨大儿、低血糖、低钙血症发生率和新生儿体质量的差异性。结果控制妊娠糖尿病孕妇血糖在理想范围后,上述观察指标之间的差异无统计学意义(P>0.05)。结论规范控制妊娠糖尿病孕妇血糖在理想范围,可以预防和减少母婴并发症的发生机会,改善围生结局。

Objective To compare the difference between the optimal control of blood glucose and the perinatal outcome of pregnant women with non gestational diabetes mellitus. Methods randomly selected in recent years glycemic control ideal of 45 cases of pregnancy in pregnant women with diabetes （observation group） and ratio of 45 cases of non maternal gestational diabetes （control group） as the research object, through the observation group of pregnant women with health education guidance, diet and exercise treatment and （or） insulin glycemic control in the ideal range, compared two groups of pregnant women with pregnancy hypertension comprehensive syndrome and preeclampsia, Caesarean birth, dystocia, and soft birth canal injury, amniotic fluid, premature rupture of membranes, postpartum hemorrhage, premature birth, neonatal respiratory distress syndrome, macrosomia, hypoglycemia, hypocalcemia occurred rate and neonatal weight difference. Results there was no significant difference in the blood glucose levels of pregnant women with diabetes mellitus （P〈0.05）. Conclusion The op-timal range of blood glucose in pregnant women with gestational diabetes mellitus can prevent and reduce the occurrence of maternal complications, improve the perinatal outcome.