糖尿病影响脑梗死的形成与颈动脉斑块相关分析

Analysis of the Formation of Diabetes Mellitus and Carotid Plaque Associated with Cerebral Infarction

目的探讨糖尿病、脑梗死与颈动脉斑块三者的相关性。方法选取苏州大学附属第二医院神经内科收治的缺血性脑血管患者139例,分别按照是否脑梗死分为脑梗死组和非脑梗死组,按照是否患糖尿病分为糖尿病组和无糖尿病组,按照颈动脉斑块的厚度分为斑块组和无斑块组,分析糖尿病、脑梗死、颈动脉斑块三者间的关系。结果脑梗死组颈动脉斑块和糖尿病阳性率均高于非脑梗死组,且斑块组的脑梗死和糖尿病阳性率也高于无斑块组,糖尿病组的脑梗死和颈动脉斑块阳性率也均高于无糖尿病组。三者相关性密切,差异有统计学意义(P<0.05)。结论颈动脉斑块易导致血栓的形成,是造成脑梗死的重要原因;而糖尿病可导致颈动脉斑块的形成,增加脑梗死的风险,在脑梗死的临床诊治中应加强合理的血糖管理。

Objective To investigate the relationship between the three patients with diabetes, cerebral infarction and carotid artery plaque. Methods Suzhou University Affiliated Second Hospital Department of Neurology, the patients with is-chemic cerebral vascular 139 cases, respectively, according to whether cerebral infarction were divided into cerebral infarc-tion group and non cerebral infarction group, according to whether diabetes were divided into diabetes group and non dia-betes groups, according to the thickness of carotid artery plaque is divided into plaque group and non plaque group. Analy-sis of relationship between diabetes, cerebral infarction, carotid artery plaque. Results The positive rate of cerebral infarc-tion patients with carotid artery plaque and diabetes mellitus were higher than those of the non cerebral infarction group, and the plaque group, the positive rate of cerebral infarction and diabetes is also higher than in the non plaque group, posi-tive rate of cerebral infarction and carotid plaques of diabetic group were also higher than that of the group without dia-betes. Three were closely related, the difference was significant （P〈0.05）, with statistical significance. Conclusion Carotid artery plaque easily lead to thrombus formation is the important reason of resulting in cerebral infarction, and diabetes can be lead to the formation of carotid plaque, cerebral infarction increased risk, in the diagnosis and treatment of cerebral in-farction should strengthen the reasonable management of blood glucose.