2型糖尿病患者合并原发性肾病综合征的临床病理分析

Clinical and Pathological Analysis on Type 2 Diabetic Patients with Primary nephrotic Syndrome

目的分析2型糖尿病患者伴原发性肾病综合征的临床病理性特点,并指出患者予以肾活检推荐指征。方法回顾性分析2012年12月—2014年12月该院8例2型糖尿病伴原发性肾病综合征患者临床资料,分析其临床病理性特点。结果 2型糖尿病伴原发性的肾小球类疾病,表现可为肾病综合征;对糖尿病的病史短、没有肾功能性不全、全身情况较好的肾病综合征,可高度显示伴原发性的肾小球类疾病存在;采用糖皮质类激素治疗的安全性高。结论若有蛋白尿、没有视网膜类病变、糖尿病的病史短等可疑的因素出现,需积极予以肾穿刺进行检查;若患者伴原发性的肾病综合征,此时糖尿病并不是予糖皮质类激素禁忌症。

Objective To analyze the clinical and pathological features of patients with type 2 diabetes mellitus with prima-ry nephrotic syndrome, and to point out the indication of renal biopsy. Methods The clinical data of 2 patients with primary nephrotic syndrome in our hospital from December December to 2012 were analyzed retrospectively. The clinical data of 8 patients with primary nephrotic syndrome were analyzed retrospectively. Results In type 2 diabetic patients with primary glomerular diseases, the performance can be as nephrotic syndrome; short history of diabetes, no renal function is not full, systemic situation better nephrotic syndrome, height display with primary glomerular diseases exist; safety uses the sugar cortical hormone treatment. Conclusion If proteinuria, no short history of retinal disease, diabetes mellitus, suspicious fac-tors appear, need to actively renal biopsy were examined; if the patients with primary nephrotic syndrome, when diabetes is not given glucocorticoids contraindications.