妇肤康喷雾剂治疗混合性阴道感染的临床研究

Clinical study of Fufukang spray treatment for mixed vaginal infections

目的:观察分析妇肤康喷雾剂治疗混合性阴道感染的临床疗效。方法:选取从2009年6月至2014年6月收治的混合性阴道感染患者共140例。随机将患者分为观察组和对照组,其中观察组患者采用妇肤康喷雾剂联合制霉素治疗,对照组患者则采用常规甲硝唑和制霉素治疗。结果:对比两组患者在停止用药14d后的复诊结果。其中BV+VVC感染观察组有效率为85.7%,对照组为66.7%;BV+TV感染观察组的治疗有效率为94.4%,对照组为64.7%;而TV+VVC感染观察组患者的治疗有效率为91.0%,对照组为72.7%;BV+VVC+TV混合感染观察组治疗有效率为92.3%,对照组为50.0%。两组患者在接受治疗后的30d复诊结果,其中BV+VVC感染观察组有效率为89.3%,对照组为50.0%;BV+TV感染观察组的治疗有效率为100%,对照组为41.2%;而TV+VVC感染观察组患者的治疗有效率为100.0%,对照组为50.0%;BV+VVC+TV混合感染观察组治疗有效率为92.3%,对照组为41.7%。对比观察组和对照组患者药物不良反应,其中观察组总体不良反应发病率为8.6%;对照组总不良反应发生率为22.9%,对比有显著性。结论:妇肤康喷雾剂能够较好治疗混合性阴道感染,不破坏阴道弱酸性环境,安全性高、复发率低,便于使用。

Objectives：To observe the clinical efficacy of Fufukang spray treatment of mixed vaginal infec-tion.Methods：140 patients with mixed vaginal infections from March 2009 to March 2014 were selected and ran-domly divided into observation group and control group,in which the observation group were treated with nystatin joint Fufukang spray treatment and the control group received conventional treatment of metronidazole and nystatin. Results：The results of subsequent visits on the 14th day after terminating treatment of both groups were compared. The BV ＋VVC infection treatment rate in the observation group and control group was 85.7% and 66.7% respec-tively;the BV ＋TV infection treatment rate in the observation group and control group was 94.4% and 64.7% re-spectively;the TV ＋ VVC infection treatment rate in the observation group and control group was 91.0 % and 72.7% respectively;the BV ＋ VVC ＋ TV mixed infection treatment rate in the observation group and control group was 92.3 % and 50.0% respectively.According to the results of subsequent visits on the 30th day after termi-nating treatment,the BV ＋VVC infection treatment rate in the observation group and control group was 89.3% and 50% respectively;the BV ＋TV infection treatment rate in the observation group and control group was 100% and 41.2% respectively;the TV ＋VVC infection treatment rate in the observation group and control group was 100%and 50% respectively;the BV ＋VVC ＋TV mixed infection treatment in the observation group and control group was 92.3 % and 41.7 % respectively.The overall incidence of adverse reactions in the observation group and control group was 8.6% and 22.9% respectively,with significant difference.Conclusions：Fufukang sprays can treat mixed vaginal infections while does not destroy the weak acid environment in vagina,which is safe and easy access with low recurrence rate.