药物流产后应用去氧孕烯炔雌醇片的疗效分析

Curative effect of marvelonon women after drug abortion

目的:分析药物流产后应用去氧孕烯炔雌醇片的疗效。方法:选取妇产科门诊拟行药物流产的早期妊娠妇女86例,随机分为观察组(43例)和对照组(43例)。两组患者均予以米非司酮联合米索前列醇终止妊娠,并予以促子宫收缩的益母草颗粒及抗生素等治疗。观察组妇女加用去氧孕烯炔雌醇片1片/d,1次/d,连用21d。对照组药物流产后除不使用去氧孕烯炔雌醇片余处理同观察组。观察并比较两组妇女阴道出血持续时间和阴道出血量、首次月经恢复情况及并发症(月经不调、宫腔积血、阵发性腹痛、盆腔炎等)的发生率。结果:观察组妇女药物流产后阴道出血持续时间明显短于对照组(P<0.05),阴道出血量明显少于对照组(χ2=12.70,P<0.01)。观察组妇女首次月经恢复时间明显短于对照组(P<0.05)。观察组妇女药物流产后总并发症发生率(4.65%)明显低于对照组(20.93%)(χ2=5.11,P<0.05)。结论:药物流产后应用去氧孕烯炔雌醇片的疗效确切,可缩短阴道出血持续时间,减少阴道出血量,有利于首次月经恢复,并能减少近期并发症发生率。

Objectives：To discuss the curative effect of Marvelon on women after drug abortion.Methods：86 early pregnant women planned to be treated with drug abortion in the outpatient of Department of Gynaecology and Obstetrics,were selected and divided into observation group （n =43 cases）and control group （n =43 cases）at random.The patients in both groups were given Mifepristone combined with Misoprostol to terminate pregnancy,and motherwort granules and antibiotics to promote uterine contraction.The women in observation group were additional-ly given Marvelon,one tablet daily,once a day for 21 days,while the women in control group were not given Marve-lon after drug abortion.The duration and amount of vaginal bleeding,the first menstruation recovery time,and the occurrence rates of complication （irregular menses,hematometra,paroxysmal abdominal pain,pelvic inflammation and etc）of women in the two groups were observed and compared.Results：The duration of vaginal bleeding after drug abortion of women in observation group was much shorter than that in control group （P 〈0.05）,and the a-mount of vaginal bleeding was much less than that in control group （χ2 =12.70,P 〈0.01）.The first menstruation recovery time of women in observation group was much shorter than that in control group （P 〈0.05）.The occur-rence rate of complication of women in observation group after drug abortion was 4.65%,which was much lower than that in control group （20.93 %）（χ2 =5.11,P 〈0.05）.Conclusions：Marvelon has reliable curative effect on women after drug abortion,which can obviously shorten the duration of vaginal bleeding,reduce vaginal bleeding amount,be favorable for the first menstruation recovery and reduce the occurrence rate of early complication.