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新生儿窒息血清胱抑素C的测定及临床意义

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摘要 目的 探讨血清胱抑素C(Cys C)的测定在新生儿窒息后肾功能损害的临床意义。方法 40例窒息新生儿(窒息组),分为轻度窒息组24例,重度窒息组16例;15例正常足月新生儿作为对照组。窒息组新生儿在入院后24 h内,对照组新生儿在出生后1~3 d抽取外周静脉血3 ml,用免疫比浊法检测各组血清Cys C水平,同时测定血清尿素氮(BUN)、肌酐(SCr)的变化,并进行统计处理。结果 与对照组相比,轻度窒息组和重度窒息组血清Cys C、BUN和SCr水平显著升高,差异有统计学意义(P〈0.05);与轻度窒息组相比,重度窒息组血清Cys C、BUN和SCr水平明显升高,差异有统计学意义(P〈0.05)。结论 血清Cys C作为窒息新生儿肾功能损伤的早期诊断指标,缺氧时间越长,肾功能损害越重。
作者 逯艳梅 曹甦
机构地区 解放军第
出处 《中国现代药物应用》 2015年第20期19-20,共2页 Chinese Journal of Modern Drug Application
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