急性缺血性脑卒中3个月预后相关影响因素

Influencing factors of three-month prognosis in acute ischemic stroke

目的探讨急性缺血性脑卒中患者3个月预后的影响因素。方法急性缺血性脑卒中患者163例,依据出院3个月后随访改良Rankin量表（Modified Rankin Scale,mRS）将其分为预后良组（mRS 0~2分）114例和预后差组（mRS 3~5分）49例。记录人口学资料、临床资料及卒中相关危险因素,对影响患者预后的因素进行单因素分析及Logistic回归分析。结果预后差组年龄、复发卒中患者比例、美国国立卫生研究院卒中量表（National Institute of Health stroke scale,NIHSS）评分高于预后良组（P〈0.05）;多因素Logistic回归分析显示,年龄、高脂血症及NIHSS评分是预后不良的危险因素（P〈0.05）。结论年龄大、有高脂血症、NIHSS评分高者急性缺血性脑卒中预后不良。

Objective To investigate the influencing factors of three-month prognosis in patients with acute ischemic stroke.Methods Acute ischemic stroke patients 163 cases,according to the follow-up Modified Rankin Scale（mRS） discharged 3 months later were divided into good prognosis group（mRS 0--2） and poor prognosis group （mRS 3--5）.The associated demographic data,clinical data and stroke-related risk factors, the factors affecting the prognosis of patients with acute ischemic stroke were analyzed by univariate analysis and multivariate logistic regression analysis.Results The age,proportion of recurrent stroke,and the NIHSS score in poor prognosis group were higher than those in good prognosis group （P〈0.05）. Logistic regression analysis showed that age, hyperlipidemia and NIHSS score were risk factors of poor prognosis （P〈0.05）.Conclusion Acute ischemic stroke patients with older age, hyperlipidemia, or higher NIHSS score have poor prognosis.