冠心病合并糖尿病患者冠状动脉造影特点

Characteristics of coronary arteriography in coronary heart disease complicated with diabetes mellitus patients

目的探讨冠心病(CHD)合并糖尿病(DM)患者冠状动脉造影的临床特点。方法 143例经冠状动脉造影确诊为冠心病患者,根据有无合并糖尿病分为DM组(62例)和非DM组(81例),比较两组患者的一般情况、血脂和冠状动脉病变范围和程度。结果两组年龄、体质量指数(BMI)、吸烟、高血压(HBP)比较,差异均无统计学意义(P>0.05),DM组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)均高于非DM组(P<0.05),DM组高密度脂蛋白胆固醇(HDL-C)低于非DM组(P<0.05),DM组冠状动脉重度狭窄、闭塞、弥漫性病变、3支及以上病变发病率高于非DM组(P<0.05)。结论 DM组冠状动脉病变累及范围广而且程度重。

Objective To investigate clinical characteristics of coronary arteriography in coronary heart disease（CHD） complicated with diabetes mellitus（DM） patients. Methods A total of 143 patients with coronary heart disease diagnosed by coronary arteriography were divided by occurrence of diabetes mellitus into DM group（62 cases） and non-DM group（81 cases）. Comparisons were made on common data, blood lipid, range and degree of coronary artery disease in the two groups. Results There were no statistically significant differences of age, body mass index（BMI）, smoking and high blood pressure（HBP） between the two groups（P〉0.05）. The DM group had all higher total cholesterol（TC）, triglyceride（TG）, and low density lipoprotein cholesterol（LDL-C） than the non-DM group（P〈0.05）. The DM group had lower high density lipoprotein cholesterol（HDL-C） than the non-DM group（P〈0.05）. The DM group had higher incidences of severe coronary stenosis, occlusion, diffuse lesion, and over 3-vessel disease than the non-DM group（P〈0.05）. Conclusion DM group has large involved range and high severity of coronary artery disease.