喹硫平对酒精所致精神障碍患者认知功能的影响

Effects of Quetiapine on cognitive function in patients with alcohol- induced mental disorders

目的:探讨喹硫平治疗酒精所致精神障碍患者对认知功能的影响。方法:选择30例酒精所致精神障碍男性患者进行喹硫平治疗,治疗前后进行P300电位测定和认知功能筛查量表(CASI)心理测量,并进行比较。结果:喹硫平治疗酒精所致精神障碍患者P300潜伏期、波幅及CASI心理测量结果与治疗前相比差异均有统计意义。结论:喹硫平能有效地改善酒精所致精神障碍患者的认知功能。

Objective：To investigate effects of Quetiapineon cognitive function in patients with alcohol-induced mental disor-ders. Methods：30 cases of patients with alcohol-induced mental disorders were selected and treated with Quetiapine. P300 potential measurement and cognitive function screening scale （ CASI） were performed before and after the treatment. Results：The differences of latency and amplitude of P300, and CASI result of the patients with alcohol-induced mental disordersbefore and after the treatmentwere statistically significant. Conclusions：The cognitive function of the patients with alcohol-induced mental disorders can be effectively improved by the use of Quetiapine.