心脉隆注射液治疗慢性心力衰竭疗效观察

Observation of Xinmailong injection on the treatment of chronic heart failure

目的观察心脉隆注射液对慢性心力衰竭(CHF)患者的治疗效果。方法将88例CHF患者随机分为2组,对照组34例予西医常规治疗,治疗组54例在对照组治疗基础上加用心脉隆注射液,5 d为1个疗程。1个疗程后比较2组治疗前后血浆氨基末端脑钠肽前体(NT-pro BNP)浓度、6 min步行距离试验(6MWT)距离变化,比较2组临床疗效。结果治疗组临床疗效优于对照组(P<0.05)。2组治疗后血浆NT-pro BNP浓度下降,6MWT距离增加,与本组治疗前比较差异均有统计学意义(P<0.05),且治疗组与对照组比较差异有统计学意义(P<0.05)。结论心脉隆注射液可明显缓解CHF患者病情,改善患者预后。

Objective To observe the curative effect of Xinmailong injection on the treatment of chronic heart failure （CHF）. Methods 88 CHF patients were randomly divided into two groups. 34 patients in control group were treated by routine western medicine treatment. 54 patients in treatment group were treated by Xinmailong injection on the basis of control group treatment. The course was 5 days. The concentration of n - terminal pro - brain natriuretic peptide （NT- proBNP） and the distance of 6 -Minute walking test （6MWT） before and after one course were observed in two groups. The clinical effect was evaluated by cardiac function changes. Results The curative effect in treatment group was superior to that in control group （ P 〈 0.05 ）. The concentration of NT - proBNP after treatment was decreased in two groups, and the distance of 6MWT was increased, and there were significant differences compared with before treatment in two groups （P 〈 0. 05 ）. There was significant difference between two groups （ P 〈0. 05 ）. Conclusion Xinmailong injection can obviously relieve the condition of CHF patients, improve the prognosis.