探讨高尔基体蛋白73及甲胎蛋白在原发性肝癌中的诊断意义

To Investigate the Diagnostic Significance of Golgi Protein 73 and AFP in Primary Hepatic Carcinoma

目的对高尔基体蛋白73(GP 73)和甲胎蛋白(AFP)在原发性肝癌中的诊断意义进行分析。方法抽取我院的原发性肝癌和良性肝脏疾病患者各100例作为A组、B组,同时抽取90例健康体检患者作为C组,利用电化学发光法和ELISA方法分别检测AFP、GP 73。结果A组的GP 73和AFP水平高于B、C组,同时GP 73和AFP共同测定原发性肝癌比单独测定的灵敏度高,P<0.05,差异具有统计学意义。结论 GP 73联合AFP检测原发性肝癌的诊断率较高。

Objective To analysis the diagnostic significance of Golgi protein 73 （ GP 73 ） and AFP in primary liver cancer. Methods Selected 100 patients with primary liver cancer and benign liver disease in our hospital were selected as A group and B group, and 90 cases of healthy physical examination were selected as C group. The AFP and GP 73 were detected by used the method of electrochemical luminescence and ELISA.Results The levels of AFP and GP 73 in A group were higher than the group C and B, and the sensitivity of AFP and GP 73 in the determination of the primary liver cancer was higher,P〈0.05, had difference statistically significance. ConclusionGP 73 combined with AFP in the diagnosis of primary liver cancer is high.